Selective N1-Alkylation of 1,3-Dibenzoylquinazoline-2,4(1H,3H)-Dione with Benzyl Chloride
نویسندگان
چکیده
منابع مشابه
Practical synthesis of potential endothelin receptor antagonists of 1,4-benzodiazepine-2,5-dione derivatives bearing substituents at the C3-, N1- and N4-positions.
The expedient synthesis of various 1,4-benzodiazepine-2,5-dione compounds, particularly those having substituents at the C3-, N1- and N4-positions is achieved. The important features in these synthetic strategies include: (i) using the coupling reaction of isatoic anhydride with alpha-amino ester for direct construction of the core structure of 1,4-benzodiazepine-2,5-dione; (ii) using potassium...
متن کامل1-Benzyl-4-chloroindoline-2,3-dione
There are two independent mol-ecules in the asymmetric unit of the title compound, C(15)H(10)ClNO(2), which differ in the dihedral angles between the mean planes of the phenyl ring and the 4-chloro-indoline-2,3-dione ring system [59.48 (9) and 79.0 (1)°]. In the crystal, mol-ecules are linked through C-H⋯O hydrogen bonds, forming polymeric chains in [100].
متن کامل1-Benzyl-6-chloroindoline-2,3-dione
In the title compound, C(15)H(10)ClNO(2),the dihedral angle between the mean planes of the benzene and 6-chloro-indoline-2,3-dione ring systems, linked through a methyl-ene group, is 81.68 (10)°. In the crystal, mol-ecules are connected by C-H⋯O hydrogen bonds, generating C(6) chains propagating in [010].
متن کامل2-Benzyl-5-methoxyisoindoline-1,3-dione
The title N-benzyl-phthalimide derivative, C16H13NO3, consists of two planar moieties, viz. the phthalimide system (r.m.s. deviation = 0.007 Å) and the phenyl ring, which make a dihedral angle of 84.7 (6)°. The meth-oxy group is almost coplanar with the phathalimide ring, as shown by the C-C-O-C torsion angle of -171.5 (2)°. In the crystal, the mol-ecules are self-assembled via non-classical C-...
متن کاملShape Selective Alkylation of Biphenyl with 1-octene on ((Al+C3H7Cl)+C2H4) Catalysts
Alkylation of biphenyl with 1-octene was investigated using ((Al+C3H7Cl)+C2H4) catalysts. The catalytic activity of ((Al+C3H7Cl)+C2H4) for the alkylation was studied at different temperatures, mol ratios of biphenyl to 1-octene, reaction times and catalyst concentrations. It was shown that using this catalyst has more advantagous than another catalysts. Experiments show that by increasing t...
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ژورنال
عنوان ژورنال: International Journal of Chemical Sciences
سال: 2018
ISSN: 0972-768X
DOI: 10.21767/0972-768x.1000279